Gut,

a leading international journal from BMJ and BSG, publishes cutting-edge gastroenterology and hepatology research and reviews

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Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis

Conclusion: Overall, our study provides evidence that Psen1 and Psen2 are important guardians of intestinal homoeostasis and future targets for barrier-promoting therapeutic strategies in IBD.

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